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We had an E coli tested on the Vitek2 that flagged positive for possible ESBL. It was resistant to Amp, Amp/Sul, Levo, and SXT. Intermediate to Cefazolin (16 mic). Ceftazidime and Ceftriaxone are /= 3 fold decrease in between the single drugs and the combination? Thank you
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Yes, it is possible. If ceftazidime and/or cefotaxime is 1.0 mcg/ml, and the corresponding drug with clavulanic acid is <=0.12, this would be a positive confirmation result for an ESBL producer. Such isolates have been reported, but remain uncommon.
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