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	If High-level AmpC production has minimal effect on the activity of cefepime, making this drug a more reliable agent for ESBL detection in the presence of an AmpC enzyme. Is reliable the routine application of the new Etest strip based on clavulanate synergy with cefepime to report esbl + for Enterobacter sp?
	The concept of the Etest based on cefepime and clavulanate is good for ESBL detection in Enterobacter spp. However, Etest concentrations may be different from those used in other methodologies. Also the mode of the organism-antibiotic encounter is a bit different from other methodologies. This means the sensitivity and specificity of the Etest method may be different from other methodologies. A good study with many types of properly-characterized ESBLs is needed to evaluate the accuracy of the Etest ESBL test based on cefepime and clavulanate.

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