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The critical identification of S. lugdunensis is in blood and other sterile body sites. Most laboratories do not identify coag negative staph to the species level when present in mixed wound cultures. However, if you are going to do a susceptibility test and report out oxacillin, you would need to know if the CNS is S. lugdunensis in order to know how to interpret the MIC or zone diameter. Do a PYR test, and if PYR+, do an ornithine test to rule in S. lug when susceptiblity is being reported.
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